‘et quid agam?’ ‘rogat! en saperdas aduehe Ponto, castoreum, stuppas, hebenum, tus, lubrica Coa. 135 tolle recens primus piper et sitiente camelo. uerte aliquid; iura.’In 1. 136, Clausen's’ adoption of et from the best manuscripts would warm the heart of A. E. Housman, who takes exception to the e, ex, and ec of other editors : ‘Spell it as you will, the preposition is not natural: the camel carried the pepper on his back, not in any of his numerous stomachs; (...) and it does not follow that we ought to say “tollere piper e camelo” because there exist such phrases as “desilire ex equo”.’ Instead, he takes both primus and sitiente camelo as adverbial adjuncts to the predicate which are parallel in force and therefore united by the conjunction et. (shrink)

This was the title of a symposium held in Moscow, May 27–30, 1986, and organized by the “International Association for the Study of Dialectical Philosophy—Societas Hegeliana,” in collaboration with the Institute for Philosophy of the Academy of Sciences of the U.S.S.R. Participation was by invitation only. Thirteen participants came from the Federal Republic of Germany, twelve from the U.S.S.R., six from the Democratic Republic of Germany, four each from France and Italy, two from Bulgaria, as well as one each from (...) Czechoslovakia, Hungary, Finland, Austria, Switzerland, Israel, Japan, the Netherlands, and Canada. Papers had been distributed previously and were briefly summarized to allow for more lengthy discussions. The two languages used were Russian and German. Simultaneous translation was provided. (shrink)

Translations, especially of important texts, tend to be controversial. In a collaborative translation, the controversy will start during the process itself, and may persist until the end. In our case this is reflected in two translators’ introductions. Translators and reviewers agree or disagree on the basis of certain principles. There are, one could say, two “schools”: those in favor of more contextual choices of terminology, and those striving for strict consistency. The first will be more inclined to distinguish between “technical” (...) and “non-technical” uses of the same term, and consider this to be part of the translator’s role. The latter will try to avoid making these distinctions, and leave as much room as possible for the reader to decide. The first also tend to see the translation as standing on its own, readily intelligible to those who are without any knowledge of the original language. The latter intend to serve primarily readers who are interested in developing some, progressively better, knowledge of the text in its original language. They will attach more importance to an extensive glossary, which ideally should be applicable to the translated author’s entire corpus. (shrink)

To show that something is “possible” or “impossible” does not seem, for Hegel, to be a genuine concern for philosophy. In point of fact, “everything is possible,” because everything has the simple form of identity-with-itself, i.e., does not contradict itself, - and it is equally true that “everything is impossible,” because, in any concrete content, the determinacy can be taken as determined opposition and so as contradiction. Hegel therefore concludes that there is “no emptier talk” than that of such “possibilities” (...) and “impossibilities”. (shrink)

Plasminogen activator inhibitor‐1 (PAI‐1) is a physiological inhibitor of urokinase (uPA), a serine protease known to promote cell migration and invasion. Intuitively, increased levels of PAI‐1 should be beneficial in downregulating uPA activity, particularly in cancer. By contrast, in vivo, increased levels of PAI‐1 are associated with a poor prognosis in breast cancer. This phenomenon is termed the “PAI‐1 paradox”. Many factors are responsible for the upregulation of PAI‐1 in the tumor microenvironment. We hypothesize that there is a breast cancer (...) predisposition to a more aggressive stage when PAI‐1 is upregulated as a consequence of Metabolic Syndrome (MetS). MetS exerts a detrimental effect on the breast tumor microenvironment that supports cancer invasion. People with MetS have an increased risk of coronary heart disease, stroke, peripheral vascular disease and hyperinsulinemia. Recently, MetS has also been identified as a risk factor for breast cancer. We hypothesize the existence of the “PAI‐1 cycle”. Sustained by MetS, adipocytokines alter PAI‐1 expression to promote angiogenesis, tumor‐cell migration and procoagulant microparticle formation from endothelial cells, which generates thrombin and further propagates PAI‐1 synthesis. All of these factors culminate in a chemotherapy‐resistant breast tumor microenvironment. The PAI‐1 cycle may partly explain the PAI‐1 paradox. In this hypothesis paper, we will discuss further how MetS upregulates PAI‐1 and how an increased level of PAI‐1 can be linked to a poor prognosis. BioEssays 29:1029–1038, 2007. © 2007 Wiley Periodicals, Inc. (shrink)

A property, F, is maximal i?, roughly, large parts of an F are not themselves Fs. Maximal properties are typically extrinsic, for their instantiation by x depends on what larger things x is part of. This makes trouble for a recent argument against microphysical superve- nience by Trenton Merricks. The argument assumes that conscious- ness is an intrinsic property, whereas consciousness is in fact maximal and extrinsic.

A property, F, is maximal iff, roughly, large parts of an F are not themselves Fs.' Maximality makes trouble for a recent analysis of intrinsicality by Rae Langton and David Lewis.

The book is a translation of my "Der rätselhafte Tod des René Descartes" (2009). It contains a rather complete collection of the documents on the fatal illness and the death of Descartes. It claims that the medical documents make a poisoning by arsenic very probable. The suspected murderer is the French monk Francois Viogué. His motive: Descartes was seen as a probable hindrance to the conversion of the Swedish queen Christina.

Die hier vorgelegten Untersuchungen nehmen ihren Aus­ gang von einem Problem, dem ich bereits in dem Vortrag "Berufsstudium und Allgemeinbildung" (1920) und dem Buche "Erkenntnis und Leben" (1923) nachgegangen bin: dem Pro­ blem nämlich, ob, inwieweit und in welchen Formen die Ar­ beit an und in der Wissenschaft der "Bildung" des ganzen Menschen dienen könne. Sie überschreiten den dort gezogenen Rahmen, indem sie sich vornehmlich mit dem Kreis von m e t a p y s h i s c h (...) e Fragestellungen n beschäftigen, der in den genannten Schriften gestreift, aber nicht als solcher in An­ griff genommen war. Insbesondere jene letzten Seinszusam­ menhänge, welche, nicht ohne Verschulden der beteiligten Fachwissenschaften, durch die vielerörterten und -beklagten Irrgänge des "Natur a 1 i s m s" u wie des sogenannten "H i­ s t o r i s m s" u verdunkelt worden sind und immer noch ver­ dunkelt werden, sollen hier in der grundsätzlichen, d. i. w i s­ s e n s c h a ich- f t 1 philosophischen Form behandelt werden, der sich die einschlägigen Erörterungen nur allzu oft zum Schaden der Sache entzogen haben. Ungesucht ergab sich in diesem Zusammenhange die Möglichkeit, einige der in meiner.. Kulturphilosophie (Individuum und Gemeinschafts, 1926) e- wickelten Gedankengänge fortzuführen und in ihre prak­ tischen Konsequenzen hinein zu verfolgen. 1. Vorwort IV Man wolle die zahlreichen Stellenangaben, die auf die hier genannten Schriften Bezug nehmen, zugleich als Hinweise auf die daselbst herangezogene sonstige LHeratur verstehen. (shrink)

Theodor Elsenhans präsentiert mit seiner Habilitationsschrift eine systematische und kritische Auseinandersetzung mit den Lehren J.F. Fries. Er unternimmt den Versuch, den extremen Realismus sowie den präempirischen Apriorismus dadurch zu überwinden, indem er die experimentelle Erzeugung von Erkenntnisformen mit dem Wissen von ihrer absoluten Gültigkeit vereint. Dieser Band umfaßt den historischen Teil, der als Vorbereitung der eigentlichen Untersuchung gilt. Er beleuchtet das Verhältnis der Friesischen Erkenntnistheorie zu derjenigen Kants kritisch-objektiv und dient nicht nur zur vollständigen Erklärung der Friesischen Philosophie, sondern trägt (...) darüber hinaus auch zum Verständnis der Kantischen Philosophie bei. Das besondere an Elsenhans Untersuchung ist, dass er darüber hinaus mit der Konstruktion einer Erkenntnistheorie aufwartet, die auf der Auseinandersetzung mit den Lehren Kants beruhen, jedoch vom Standpunkt der Problemstellung seitens Fries erfolgen. (shrink)

This paper discusses alternative measures of assortative matching and relates them to Sewall Wright’s F-statistic. It also explores applications of measures of assortativity to evolutionary dynamics. We generalize Wright’s statistic to allow the possibility that some types match more assortatively than others, and explore the possibility of identifying parameters of this more general model from the observed distribution of matches by the partners’ types.

In lieu of an abstract, here is a brief excerpt of the content:THE START OF METAPHYSICS* THEODORE J. KoNDOLEON Villanova University Villanova, Pennsylvania I N HIS RECENTLY published book, John F. X. Knasas seeks to answer this twofold inter-related question: What, according to Saint Thomas's expressed teaching, is the subject of metaphysics and how does the human mind proceed to attain it for the purpose of study? While he acknowledges a debt to Joseph Owens for certain of his basic (...) positions, Knasas will claim that the book's argument is original in the way in which it opposes what he takes as realistically the subject of metaphysics at its initial stage (or with the only understanding of beingens -metaphysics requires to begin) to what will become this science 's subject at its later, more mature stage. Moreover, although he may contradict himself on this point, he will reject, as Saint Thomas's view, the position that a physical demonstration can establish the existence of immaterial being, be it God or angels. He will also argue at some length what he evidently considers a crucial epistemic procedure for the start of metaphysics, viz., that a series of judgments relating individuals back to their acts of existence (from whence they were originally abstracted) is required for the "judgmentally constituted multitude" from which the mind attains common being. Finally, since he will insist that abstraction must be controlled by the data, he will allow no room in Thomistic metaphysics for a beginning metaphysical intuition in which being is seen as not necessarily linked to matter and motion, nor for an a priori approach to its subject which would start *John F. X. Knasas, The Preface to Metaphysics: A Contribution to the N eo-Thomist Debate on the Start of Metaphysics. New York: Peter Lang, 1990. Pp. 193. 121 122 THEODORE J. KONDOLEON from the nature of the knowing subject, viz., the human intellect, as open to and directed toward infinite being and intelligibility. In what follows I will discuss (and critically assess) each of these features of this book as well as address myself briefly to certain things the author has to say about the Thomistic " five ways." In the first three chapters Knasas is primarily concerned with showing that metaphysics cannot begin with a notion of being understood in the sense of ens commune. This sense of the notion traditionally includes both material and immaterial being. However, he argues, since (according to his reading of Aquinas) only metaphysics can demonstrate the existence of immaterial being, its subject cannot, at least at its outset, encompass such being, not even as something conceivable. He therefore opposes the view of Neo-Thomists who, basing themselve? on the now famous and frequently cited text from Saint Thomas's Expositio on Boethius's De Trinitate (Question 5, article 3), insist that metaphysics begins with the recognition that being is something separate from matter and motion (and not merely so in the mind's consideration by abstraction). This separation is understood in the so-called negative judgment of separation: " it is not of the nature of being to be in matter and motion (even though it is sometimes found therein)." On this point Knasas finds fault with " Natural Philosophy" Thomists, among whom he includes the Dominicans L.-B. Geiger (although this writer is barely mentioned and only in a footnote discussion) and James Weisheipl, both of whom have argued that the subject of metaphysics presupposes a demonstration from natural philosophy that immaterial, unchanging being exists (otherwise, they maintain, the separation of which Saint Thomas speaks in the De Trinitate Commentary would have no fundamentum in re). Again, his main argument with these Thomists is that no textual justification can be found for their view-indeed there is counter-textual evidence against it-that physical philosophy proves the existence of immaterial being and that, in the eyes of Aquinas, metaphysics awaits such a demonstration in order to begin. He equally rejects the position, one which he at- THE START OF METAPHYSICS 123 tributes above all to Maritain, that, prior to any argument that would establish the actual existence of God, being can be understood -and this thanks to an existential judgment in which existence is restored to the essence... (shrink)

I am now typing on a computer I bought two years ago. The computer I bought is identical to the computer on which I type. My computer persists over time. Let us divide our subject matter in two. There is first the question of criteria of identity, the conditions governing when an object of a certain kind, a computer for instance, persists until some later time. There are secondly very general questions about the nature of persistence itself. Here I include (...) the question of temporal parts, as well as certain familiar paradoxes (e.g., the statue and the lump). Following John Perry (1975, Introduction), let us characterize a criterion of identity over time for F s as a way of filling in φ in the following schema: Stages S1 and S2 belong to some continuing F iff φ Defenders of temporal parts (see below) regard S1 and S2 as being temporal parts of the continuing F ; others regard S1 and S2 as different stages in the life history of the continuing F . Thus each camp can make use of Perry’s formula. It is traditional to divide such criteria into those governing persons and those governing anything else. It is further traditional to say that the criterion of identity over time for non-persons involves spatiotemporal continuity. An excellent discussion is Eli Hirsch’s The Concept of Identity1, which utilizes the notion of continuity under a sortal. Kind-terms, or sortals, are terms that specify what kind of or sort of thing an object is. Examples include ‘tree’, ‘car’, and ‘mountain’. Where F is a sortal, Hirsch’s analysis is roughly that stages belong to the same F iff they are connected by a spatiotemporally and qualitatively continuous sequence of F -stages. Unmodified, this analysis prohibits temporally discontinuous entities, such as a watch that is taken apart and then reassembled. Hirsch discusses the necessary modifications. Spatiotemporal continuity analyses face a problem when applied to the persistence of matter. The literature here has been dominated by discussion of examples provided by David Armstrong (1980) and Saul Kripke (unpublished.... (shrink)

Ten arguments for the nonexistence of God are formulated and discussed briefly. Each of them ascribes to God a pair of properties from the following list of divine attributes: (a) perfect, (b) immutable, (c) transcendent, (d) nonphysical, (e) omniscient, (f) omnipresent, (g) personal, (h) free, (i) all-loving, (j) all-just, (k) all-merciful, and (1) the creator of the universe. Each argument aims to demonstrate an incompatibility between the two properties ascribed. The pairs considered are: 1. (a-1), 2. (b-1), 3. (b-e), 4. (...) (b-i), 5, (c-f), 6. (c-g), 7. (d-g), 8. (f-g), 9. (e-h), and 10. (j-k). Along the way, several other possible pairs are also mentioned and commented upon. (shrink)

In this paper i offer a detailed analysis of the dilemma of participation (parmenides, 130e-131e), in which plato considers the consequences of participation in the whole, and in a part of, a form. This analysis explains, in contrast to existing interpretations of the argument, plato's claim that participation in parts of a form is incompatible with the uniqueness of the form, and his modal claim that becoming equal by possessing part of the equal is absurd. In the second part of (...) the paper, i give the premisses and logical steps of the third man argument in the parmenides, and show the premisses to be committed to absurdity, even without the assumption that there is a unique form per character f. (shrink)

In this paper I provide some formal schemas for the analysis of vague predicates in terms of a set of semantic relations other than classical synonymy, including weak synonymy (as between "large" and "huge"), antonymy (as between "large" and "small"), relativity (as between "large" and "large for a dog"), and a kind of supervenience (as between "large" and "wide" or "long"). All of these relations are representable in the simple comparative logic CL, in accordance with the basic formula: the more (...) something is F, the more (or less) it is G. I use Carnapian meaning postulates to define these relations as constraints on interpretations of the formal language of CL. (shrink)

Preface By Hoxie N. Fairchild, Bruce M. Bigelow, Albert C. Outler, Edmund W. Sinnott, George F. Thomas And Robert Ulich.

Although there is much scholarship on Maurice Blanchot’s relationship to his contemporaries on the French intellectual scene, substantially less has been made of his debts to the German philosophical heritage in general, and to G. W. F. Hegel in particular. In this article, the author maintains that Blanchot’s association of literature with worklessness comprises a direct, if somewhat tacit, refusal of Hegel’s determination of art as a work of spirit. The author argues that Blanchot’s critical relation to Hegel sheds new (...) light not only on Blanchot’s conception of literature and related themes of language, but also on his view of the significance of literature as a powerful and elusive force of resistance to hegemonic and ideological programs of many kinds. (shrink)

It is remarkable how many journalists embrace the principles of public journalism but fail to recognize the importance of applying those principles to journalism itself. While the press stands ready to expand the opportunities for public debate by inviting everyone to participate, journalists typically exempt themselves by declining invitations others are expected to accept. I f indeed the press plays a vitally important role in creating and maintaining the conditions for selfgovernance, as journalists claim whenever they raise the banner of (...) public journalism, the press needs to assume responsibility for-and invite commenta y on-the quality of its performance and the integrity of its practices. In short, the press needs to recognize itself as a distinctively public institution bound by the same standards of accountability expected of other public institutions. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:Art Subjects: Making Artists in the American UniversityTheodore GracykArt Subjects: Making Artists in the American University, by Howard Singerman. Berkeley, Los Angeles, London: University of California Press, 1999, 296 pp., $19.95 paper.Howard Singerman's Art Subjects is a study of the training of visual artists in American universities from 1912 to the present. More precisely, the book is an account of how two philosophies ofeducation have competed to inform (...) that training. At the outset, Singerman announces that the book explores a long-standing "struggle between vision and language" (p. 10) that culminates with a decisive privileging of language. The book mimics its putative subject in at least one interesting way. As it was for art and the training of American artists in the twentieth century (at least on Singerman's account of them), so it is with the book. Each moves from a practice grounded in objective reality to a jargon-ridden discourse that limits entry to anyone outside of its acutely self-regarding disciplinary field. Although the book's acknowledgments segment thanks one individual for demanding thatSingerman "come to a real conclusion" for the book, readers should note Singerman's subsequent admission that it may not have one. At times it even appears that Singerman goes out of his way to avoid drawing one.Art Subjects appears to have started life as Singerman's doctoral dissertation, but it only occasionally displays the dull by-the-numbers writing of such documents. The book has a clear organization and its numerous quotations are carefully documented. The overall argument is framed, beginning and end, with Singerman's autobiography of his own time as a university art student. It provides him with his framing question: if he has a M.F.A. in sculpture but never learned to sculpt, what does his professional degree signify? The answer is that it indicates that his work is no longer facile. He has progressed from the realm of the artist whose work is professional, displaying facility, to the stage where he is professional. He has progressed to the point where being an artist is theartist's true subject: "Artists are the subject of graduate school; they are both who and what is taught" (p. 3). If this progression is best indicated by an artist's lack of facility in producing works of art, that is the price of professionalism. In the post-World War II university, art training is "founded on the primacy of theory over practice" (p. 181). Yet the result is professionalism without a clear profession other than as an employee of the post-World War II university: the M.F.A. prepares artists for the university discipline of art. Citing Foucault, Singerman seems satisfied that artists have taken command of a theoretical field. Disciplinary boundaries are created and policed by its rules of professional discourse. At the same time, Singerman declares his intention to "use the concept of the discipline as it constrains and structures discourses to keep from having to judge whether or not art is a profession" (p. 201). He likewise mentions [End Page 119] but does not take any stand on the "putative decline of recent art" (p. 210). This ongoing refusal to judge deprives the book of potentially interesting conclusions. It also calls into question Singerman's repeated references to the "self-criticality" of the discipline.Singerman's neutrality might berefreshing were it not for his use of Foucault to introduce the notion that each new "proposition" within the disciplinary discourse represents progress in a "theoretical field," moving "knowledge" forward. Talking about art (and not, to be sure, talking all that much about specific works of art) and talking about being an artist may or may not represent progress. For instance, Singerman's early chaptersmake the case that the triumph of artistic modernism must be understood as a repudiation of a "female" aesthetic and even of women as artists. Singerman returns to the topic ofwomen artists only once, to note Griselda Pollock's approval of the entry of feminism into the academic discipline of art. Thus Singerman is silent on the question of whether progress is made when the number of women is... (shrink)

We show that, for every partition F of the pairs of natural numbers and for every set C, if C is not recursive in F then there is an infinite set H, such that H is homogeneous for F and C is not recursive in H. We conclude that the formal statement of Ramsey's Theorem for Pairs is not strong enough to prove , the comprehension scheme for arithmetical formulas, within the base theory , the comprehension scheme for recursive formulas. (...) We also show that Ramsey's Theorem for Pairs is strong enough to prove some sentences in first order arithmetic which are not provable within . In particular, Ramsey's Theorem for Pairs is not conservative over for -sentences. (shrink)